Peer-reviewed Papers

  • Santini, F. The scientific system must bend to avoid breaking. Eur Radiol (2024). doi: 10.1007/s00330-024-10691-x
  • Koch D, Nüesch C, Ignasiak D, Aghlmandi S, Caimi A, Perrot G, Prüfer F, Harder D, Santini F, Schären S, Ferguson S, Mündermann A, Netzer C. The role of muscle degeneration and spinal balance in the pathophysiology of lumbar spinal stenosis: Study protocol of a translational approach combining in vivo biomechanical experiments with clinical and radiological parameters. PLoS ONE 2023;18:e0293435 doi: 10.1371/journal.pone.0293435.
  • Wang F*, Fang S, Li J, Yuan L, Hou B, Zhu J, Jiao Y, Liu Z, Qian M*, Santini F*, Wang Q, Chen L, Feng F. Correlation analysis of quantitative MRI measurements of thigh muscles with histopathology in patients with idiopathic inflammatory myopathy. Eur Radiol Exp 2023;7:51 doi: 10.1186/s41747-023-00350-z. * Corresponding Authors
  • Afshari R, Santini F, Heule R, Meyer CH, Pfeuffer J, Bieri O. Rapid whole-brain quantitative MT imaging. Zeitschrift für Medizinische Physik (2023). 10.1016/j.zemedi.2023.02.005.
  • Colelli, G., Barzaghi, L., …, Deligianni, X., Santini, F.,et al. Radiomics and machine learning applied to STIR sequence for prediction of quantitative parameters in facioscapulohumeral disease. Frontiers in Neurology, 14 (2023). 10.3389/fneur.2023.1105276
  • Kentgens, A.-C., Pusterla, O., Bauman, G., Santini, F., Wyler, F., Curdy, M. S., Willers, C. C., Bieri, O., Latzin, P., & Ramsey, K. A.. Simultaneous Multiple Breath Washout And Oxygen-Enhanced Magnetic Resonance Imaging In Healthy Adults. Respiratory Medicine and Research, 100993 (2023). 10.1016/j.resmer.2023.100993
  • Lin, Y.-S., Weibel, J., Landolt, H.-P., Santini, F., Slawik, H., Borgwardt, S., Cajochen, C., & Reichert, C. F.. Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: A randomized double-blind placebo-controlled trial. Scientific Reports, 13(1), Article 1 (2023). 10.1038/s41598-022-26808-5
  • Monforte, M., Attarian, S., … Santini F., et al., 265th ENMC International Workshop: Muscle imaging in Facioscapulohumeral Muscular Dystrophy (FSHD): relevance for clinical trials. 22–24 April 2022, Hoofddorp, The Netherlands. Neuromuscular Disorders, 33(1), 65–75 (2023). 10.1016/j.nmd.2022.10.005
  • Holman R, Lorton O, Guillemin PC, Desgranges S, Santini F, Preso DB, Farhat M, Contino-Pépin C, Salomir R, Perfluorocarbon emulsion enhances MR-ARFI displacement and temperature in vitro: evaluating the response with MRI, NMR, and hydrophone, Frontiers in Oncology (2023). 10.3389/fonc.2022.1025481
  • Wang F, Zhou S, Hou B, Santini F*, Yuan L, Guo Y, Zhu J, Hilbert T, Kober T, Zhang Y, Wang Q, Zhao Y, & Jin Z*, Assessment of idiopathic inflammatory myopathy using a deep learning method for muscle T2 mapping segmentation, European Radiology (2022), 10.1007/s00330-022-09254-9 *Corresponding Author
  • Vegezzi E, Cortese A, Bergsland N, Santini F, et al. Muscle quantitative MRI as a novel biomarker in hereditary transthyretin amyloidosis with polyneuropathy: a cross-sectional study. J Neurol (2023). 10.1007/s00415-022-11336-z
  • Deligianni, X., Santini, F., Paoletti, M., Solazzo, F., Bergsland, N., Savini, G., Faggioli, A., Germani, G., Monforte, M., Ricci, E., Tasca, G., & Pichiecchio, A. Dynamic magnetic resonance imaging of muscle contraction in facioscapulohumeral muscular dystrophy. Scientific Reports, 12(1), 7250 (2022). 10.1038/s41598-022-11147-2
  • Pusterla O, Heule R, Santini F, et al., MRI lung lobe segmentation in pediatric cystic fibrosis patients using a recurrent neural network trained with publicly accessible CT datasets, Magn. Reson. Med., 2022, doi: 10.1002/mrm.29184
  • Lin Y-S, Weibel J,… Santini F, et al., Time to recover from daily caffeine intake, Frontiers in Nutrition 2022, doi: 10.3389/fnut.2021.787225
  • Diaz-Manera J, Pichiecchio A, Santini F, Filosto M, Editorial: Imaging of Neuromuscular Diseases, Frontiers in Neurology 2021, doi: 10.3389/fneur.2021.814579
  • Agosti A, Shaqiri E, … Santini F, et al. Deep learning for automatic segmentation of thigh and leg muscles, Mag. Reson. Mater. Phy. 2021, doi: 10.1007/s10334-021-00967-4
  • Paoletti M, Diamanti L, … Santini F, et al. Longitudinal Quantitative MRI Evaluation of Muscle Involvement in Amyotrophic Lateral Sclerosis, Frontiers in Neurology 2021, doi: 10.3389/fneur.2021.749736
  • Williams G, Thyagarj S, … Santini F, et al., In vitro evaluation of cerebrospinal fluid velocity measurement in type I Chiari malformation: repeatability, reproducibility, and agreement using 2D phase contrast and 4D flow MRI, Fluids and Barriers of the CNS 18, 12 (2021), doi: 10.1186/s12987-021-00246-3
  • Weidensteiner C, Madoerin P, … Santini F, et al., Quantification and monitoring of the effect of botulinum toxin A on paretic calf muscles of children with cerebral palsy with MRI: a preliminary study, Frontiers in Neurology 2021, doi: 10.3389/fneur.2021.630435
  • Savini G, Asteggiano C, …Santini F, et al. , Pilot study on quantitative cervical cord and muscular MRI in spinal muscular atrophy: promising biomarkers of disease evolution and treatment?, Frontiers in Neurology 2021, doi: 10.3389/fneur.2021.613834
  • Akinci D’Antonoli T, Santini F, Deligianni X, et al., Combination of Quantitative MRI Fat Fraction and Texture Analysis to Evaluate Spastic Muscles of Children with Cerebral Palsy, Frontiers in Neurology 2021, doi: 10.3389/fneur.2021.633808
  • Santini F, Deligianni X, Paoletti M, et al., Fast open-source toolkit for water T2 mapping in the presence of fat from multi-echo spin-echo acquisitions for muscle MRI, Frontiers in Neurology 2021, doi: 10.3389/fneur.2021.630387.
  • Lin YS, Weibel J, Landolt HP, Santini F, et al, Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial, Cerebral Cortex 2021, doi: 10.1093/cercor/bhab005
  • Afshari R, Santini F, Heule R, et al., One-Minute Whole-Brain Magnetization Transfer Ratio Imaging with Intrinsic B1-Correction, Magn Reson Med 2020, doi: 10.1002/mrm.28618
  • Felisaz PF, Colelli G, … Santini F, Deligianni X, et al., Texture analysis and machine learning to predict water T2 and fat fraction from non-quantitative MRI of thigh muscles in Facioscapulohumeral muscular dystrophy, Eur. J. Radiol. 2020, doi: 10.1016/j.ejrad.2020.109460
  • Deligianni X, Hirschmann A, Place N, Bieri O, Santini F, Dynamic MRI of plantar flexion: A comprehensive repeatability study of electrical stimulation-gated muscle contraction standardized on evoked force, PLoS One 2020, doi: 10.1371/journal.pone.0241832
  • Santini F, Pansini M, Hrabak-Paar M, et al. On the optimal temporal resolution for phase contrast cardiovascular magnetic resonance imaging: establishment of baseline values, J Cardiovasc Magn Reson 22, 72 (2020). doi: 10.1186/s12968-020-00669-1
  • Felisaz PF, Belatti E, Deligianni X, Bergsland N, Santini F, et al. , Variable echo time imaging for detecting the short T2* components of the sciatic nerve: a validation study, Magn Reson Mater Phy 2020, doi: 10.1007/s10334-020-00886-w
  • Willers C, Bauman G, Andermatt S, Santini F, et al. , The impact of segmentation on whole‐lung functional MRI quantification: Repeatability and reproducibility from multiple human observers and an artificial neural network, Magn Reson Med 2020, doi: 10.1002/mrm.28476
  • Hrabak-Paar M, Kircher A, Al Sayari S, Kopp S, Santini F, et al., Variability of MRI Aortic Stiffness Measurements in a Multicenter Clinical Trial Setting: Intraobserver, Interobserver, and Intracenter Variability of Pulse Wave Velocity and Aortic Strain Measurement, Radiology: Cardiothoracic Imaging 2020, doi: 10.1148/ryct.2020190090
  • Santini F, Gui L, Lorton O, et al. Ultrasound-driven Cardiac MRI, Physica Medica: European Journal of Medical Physics 2020;70:161–168 doi: 10.1016/j.ejmp.2020.01.008.
  • Deligianni X, Klenk C, Place N, … Santini F, Dynamic MR imaging of the skeletal muscle in young and senior volunteers during synchronized minimal neuromuscular electrical stimulation. Magn Reson Mater Phy 2019 doi: 10.1007/s10334-019-00787-7.
  • Willers CC, Pusterla O, Bauman G, …, Santini F, et al. Inter-reader variation in lung segmentation of functional lung MRI quantification. European Respiratory Journal 2019;54 doi: 10.1183/13993003.congress-2019.PA333.
  • Altermatt A, Santini F, Deligianni, X, et al. Design and construction of an innovative brain phantom prototype for MRI. Magn Reson Med. 2019; 81: 1165– 1171. doi: 10.1002/mrm.27464
  • Strijkers, GJ, …. Santini F, … et al., Exploration of New Contrasts, Targets, and MR Imaging and Spectroscopy Techniques for Neuromuscular Disease – A Workshop Report of Working Group 3 of the Biomedicine and Molecular Biosciences COST Action BM1304 MYO-MRI, Journal of Neuromuscular Diseases 2019, 6(1): 1-30
  • Santini, F, Bieri, O, Deligianni, X, OpenForce MR: A low-cost open-source MR-compatible force sensor, Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering 2018, 48(4), e21404
  • Bauman, G., Pusterla, O., Santini, F. and Bieri, O., Dynamic and steady-state oxygen-dependent lung relaxometry using inversion recovery ultra-fast steady-state free precession imaging at 1.5 T. Magn. Reson. Med 2018, 79: 839–845. doi:10.1002/mrm.26739
  • Pusterla, O., Sommer, G., Santini, F., Wiese, M., Lardinois, D., Tamm, M., Bremerich, J., Bauman, G. and Bieri, O., Signal enhancement ratio imaging of the lung parenchyma with ultra-fast steady-state free precession MRI at 1.5T. J. Magn. Reson. Imaging 2018. doi:10.1002/jmri.25928
  • Celicanin Z, Manasseh G, Petrusca L, Scheffler K, Auboiroux V, Crowe LA, Hyacinthe J-N, Natsuaki Y, Santini F, Becker ChD, Terraz S, Bieri O, Salomir R, Hybrid ultrasound‐MR guided HIFU treatment method with 3D motion compensation, Magn. Reson Med 2017, doi:10.1002/mrm.26897
  • Sigg SJ, Santini F, Najer A, Richard PU, Meier WP, Palivan CG, Nanoparticle-based highly sensitive MRI contrast agents with enhanced relaxivity in reductive milieu, Chem. Commun., 2016, Advance Article, DOI: 10.1039/C6CC03396B
  • Deligianni X, Pansini M, Garcia M, Hirschmann A, Schmidt-Trucksäss A, Bieri O, Santini F. Synchronous MRI of muscle motion induced by electrical stimulation. Magn Reson Med 2016. doi: 10.1002/mrm.26154.
  • Sinanaj I, Montandon M-L, Rodriguez C, Herrmann F, Santini F, Haller S, Giannakopoulos P. Neural underpinnings of background acoustic noise in normal aging and mild cognitive impairment. Neuroscience 310:410–421, 2015.
  • Barandun M, Iselin LD, Santini F, Pansini M, Scotti C, Baumhoer D, Bieri O, et al., Generation and Characterization of Osteochondral Grafts with Human Nasal Chondrocytes, Journal of Orthopaedic Research, 33, no. 8 August: 1111–19, 2015
  • Schubert T, Pansini M, Bieri O, Stippich Ch, Wetzel S, Schaedelin S, von Hessling A, Santini F, Attenuation of Blood Flow Pulsatility along the Atlas Slope: A Physiologic Property of the Distal Vertebral Artery?, AJNR Am J Neuroradiol.Mar;36(3):562-7, 2015
  • Santini F, Kawel-Boehm N, Greiser A, Bremerich J, Bieri O, Simultaneous T1 and T2 quantification of the myocardium using cardiac balanced-SSFP inversion recovery with interleaved sampling acquisition (CABIRIA). Magn Reson Med, 74: 365–371, 2015.
  • Celicanin Z, Bieri O, Preiswerk F, Cattin Ph, Scheffler K, Santini F, Simultaneous acquisition of image and navigator slices using CAIPIRINHA for 4D MRI, Magn Reson Med, 73: 669–676, 2015.
  • Kawel-Böhm N, Dellas Buser Th, Greiser A, Bieri O, Bremerich J, Santini F, In-vivo assessment of normal T1 values of the right-ventricular myocardium by cardiac MRI, International Journal of Cardiovascular Imaging, Feb;30(2):323-8, 2014
  • Celicanin Z, Auboiroux V, Bieri O, Petrusca L, Santini F, Viallon M, Scheffler K, Salomir R., Real-time method for motion-compensated MR thermometry and MRgHIFU treatment in abdominal organs. Magn Reson Med.Oct;72(4):1087-95, 2014
  • Schubert T, Bieri O, Stippich Ch, Santini F, Peak Velocity Measurements in Tortuous Arteries with Phase Contrast MRI: The Effect of Multidirectional Velocity Encoding, Investigative Radiology, Apr;49(4):189-194, 2014.
  • Del Grande F, Santini F, Herzka DA, Aro AR, Dean CW, Gold GE, Carrino JA, Fat-suppression techniques for 3-T MR imaging of the musculoskeletal system. Radiographics, vol. 34, no. 1, pp. 217–233, Feb. 2014.
  • Petrusca L, Cattin P, De Luca V, Preiswerk F, Celicanin Z, Auboiroux V, Viallon M, Arnold P, Santini F, Terraz S, Scheffler K, Becker CD, Salomir R., Hybrid ultrasound/magnetic resonance simultaneous acquisition and image fusion for motion monitoring in the upper abdomen, Invest Radiol. May;48(5):333-40, 2013
  • Meckel S, Leitner L, Honati LH, Santini F, Schubert T, Stalder AF, Lyrer Ph, Markl M, Wetzel SG, Intracranial Artery Flow Measurement Using Flow-Sensitized 4D MR Imaging at 3T: Validation with Transcranial Ultrasound Techniques and 2D PC MR Imaging Neuroradiology,. Mar;55(4):389-98, 2013
  • Ganter C, Settles M, Dregely I, Santini F, Scheffler K, Bieri O, B1+-mapping with the transient phase of unbalanced steady-state free precession, Magn Reson Med. Feb 4, 2013
  • Kawel N, Santini F, Haas T, Zellweger MJ, Streefkerk HJ, Bremerich J, Normal response of cardiac flow and function to adenosine stress as assessed by cardiac MR, J Cardiovasc Med (Hagerstown). Nov;13(11):720-6, 2012
  • Kawel N, Santini F, Haas T, Froelich JM, Bremerich J, The protein binding substance Ibuprofen does not affect the T1 time or partition coefficient in contrast-enhanced cardiac magnetic resonance imaging, Journal of Cardiovascular Magnetic Resonance,Oct 15;14:71, 2012
  • Kawel N, Nacif M, Santini F, Liu S, Bremerich J, Arai A, Bluemke DA, Partition coefficient for gadolinium in the normal myocardium: Comparison of Gadopentetate dimeglumine and Gadobenate dimeglumine, Journal of Magnetic Resonance Imaging, Sep;36(3):733-7, 2012
  • Zecca C, Cereda C, Wetzel S, Tschuor S, Staedler C, Santini F, Nadarajah N, Bassetti CL, Gobbi C, Diffusion-weighted imaging in acute demyelinating myelopathy, Neuroradiology, Jun;54(6):573-8, 2012
  • Anders J, SanGiorgio P, Deligianni X, Santini F, Scheffler K, Boero G, Integrated active tracking detector for MRI-guided interventions, Magnetic Resonance in Medicine, 67: 290–296, 2012
  • Papadimitropoulos A, Scherberich A, Güven S, Theilgaard N, Crooijmans HJA, Santini F, Scheffler K, Zallone A, Martin I, A 3D in vitro bone organ model using human progenitor cells, eCells&Materials, 2011 Volume No 21 – p445-458
  • Schubert T, Santini F, Stalder AF, Bock J, Meckel S, Bonati L, Markl M, Wetzel S, Dampening of Blood-Flow Pulsatility along the Carotid Siphon: Does Form Follow Function? AJNR Am J Neuroradiol. 2011 Apr 7
  • Santini F, Patil S, Scheffler K, IceLuva: A scripting framework for MR image reconstruction based on free software, Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering, 39B: 1–10, 2011.
  • Paysan P, Lüthi M, Albrecht T, Lerch A, Amberg B, Santini F, Vetter T, Face Reconstruction from Skull Shapes and Phyical Attributes, DAGM-Symposium 2009: 232-241
  • Santini F, Wetzel SG, Bock J, Markl M, Scheffler K, Time-resolved three-dimensional (3D) phase-contrast (PC) balanced steady-state free precession (bSSFP), Magn Reson Med. 2009 Oct;62(4):966-74.
  • Meckel S, Stalder A, Santini F, Radü EW, Rüfenacht DA, Markl M, Wetzel SG, In-vivo Visualization and Analysis of 3D Hemodynamics in Cerebral Aneurysms with Flow-sensitized 4D MR Imaging at 3T, Neuroradiology. 2008 Jun;50(6):473-84.
  • Santini F, Patil S, Meckel S, Scheffler K, Wetzel SG. Double-reference cross-correlation algorithm for separation of the arteries and veins from 3D MRA time series. Journal of Magnetic Resonance Imaging. 2008 ;28(3):646-654.